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This study demonstrates that exogenous spermidine (Spd) enhances alkaline-salt stress tolerance in potato (Solanum tuberosum) by enhancing antioxidant defenses, maintaining osmotic balance, and inducing tissue-specific transcriptional reprogramming. RNA-seq and WGCNA identified key pathways including plant hormone signaling and carbon metabolism, along with candidate hub genes (StHK4, StbZIP27, and StERF106) that act as potential regulators of Spd-induced stress adaptation.
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An AI-powered Knowledge Hub for Potato Functional Genomics, Plant Commun., 10.1016/j.xplc.2026.101730